Histopathological features of liver tissue in non-alcoholic and alcoholic steatohepatitis depending on the presence of concomitant anemia

The aim: to study some histopathological changes in the liver affected by steatohepatitis of various etiologies with presence anemia. Material and methods. Liver biopsies were analyzed 30 patients non-alcoholic (NASH) 20 alcoholic (ASH). morphological examination was carried out according standard features established on basis hematoxylin eosin staining method, confirmation, if necessary, histochemical methods - for fat (method Sudan-III) collagen fibers chromotropic-water blue NZ Slinchenko). Microspectrophotometric studies performed using a cytological analyzer software "VideoTest Size 5.0" (2000). Results. A number parameters revealed statistical differences average trends use nonparametric Mann-Whitney method (p<0.05). highest rate hepatocyte necrosis observed ASH anemia, particular, more than third hepatocytes these had signs colic necrosis, which pronounced NASH. NASH anemia accompanied without In percentage approximately same as Fatty dystrophy all ASH, but severity general pathological process not same. Conclusions. Due comorbidity fatty disease both much higher reversible swelling are formed, coincides tendency oncosis. Anemia affects nature connective tissue growth (in specific volume NASH). At time, intensity regenerative processes (ductal reactions liver) is most ASH.